Open AccessEpigenetics in acute kidney injury
Author(s) -
Jinhua Tang,
Songlin Zhuang
Publication year - 2015
Publication title -
current opinion in nephrology and hypertension/current opinion in nephrology and hypertension, with evaluated medline
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.158
H-Index - 95
eISSN - 1080-8221
pISSN - 1062-4821
DOI - 10.1097/mnh.0000000000000140
Subject(s) - epigenetics , acute kidney injury , histone , microrna , dna methylation , acetylation , kidney , medicine , methylation , pathogenesis , bioinformatics , cancer research , biology , gene expression , pathology , gene , genetics
Recent advances in epigenetics indicate the involvement of several epigenetic modifications in the pathogenesis of acute kidney injury (AKI). The purpose of this review is to summarize our understanding of recent advances in the epigenetic regulation of AKI and provide mechanistic insight into the role of acetylation, methylation, and microRNA expression in the pathological processes of AKI.