Association between adherence to concomitant proton pump inhibitor therapy in current NSAID users and upper gastrointestinal complications | Zendy

Christian Jonasson | Zendy; Jan Gunnar Hatlebakk | Zendy; Lars Lundell | Zendy; Jukka Pekka Kouri | Zendy; Morten Andersen | Zendy; Fredrik Granath | Zendy

Open Access

Association between adherence to concomitant proton pump inhibitor therapy in current NSAID users and upper gastrointestinal complications

Author(s) -

Christian Jonasson,

Jan Gunnar Hatlebakk,

Lars Lundell,

Jukka Pekka Kouri,

Morten Andersen,

Fredrik Granath

Publication year - 2012

Publication title -

european journal of gastroenterology and hepatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.881

H-Index - 102

eISSN - 1473-5687

pISSN - 0954-691X

DOI - 10.1097/meg.0b013e32835d5acd

Subject(s) - medicine , odds ratio , proton pump inhibitor , concomitant , medical prescription , confidence interval , observational study , population , logistic regression , peptic , gastroenterology , peptic ulcer , pharmacology , environmental health

Proton pump inhibitors (PPIs) play a well-documented role as a gastroprotective agent among NSAID users at an increased risk of peptic ulcer and bleeding. Observational studies have, however, suggested that the clinical efficacy of PPI therapy may be reduced because of poor adherence.

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