Open AccessLecithin: cholesterol acyltransferase – from biochemistry to role in cardiovascular disease
Author(s) -
Xavier Rousset,
Boris Vaisman,
Marcelo Amar,
Amar A. Sethi,
Alan T. Remaley
Publication year - 2009
Publication title -
current opinion in endocrinology, diabetes and obesity./current opinion in endocrinology, diabetes and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.199
H-Index - 67
eISSN - 1752-2978
pISSN - 1752-296X
DOI - 10.1097/med.0b013e328329233b
Subject(s) - lecithin—cholesterol acyltransferase , sterol o acyltransferase , lecithin , disease , apolipoprotein b , cholesterol , medicine , pathogenesis , endocrinology , lipoprotein , lipid metabolism , apolipoprotein e , population , acyltransferase , biology , biochemistry , enzyme , environmental health
We discuss the latest findings on the biochemistry of lecithin : cholesterol acyltransferase (LCAT), the effect of LCAT on atherosclerosis, clinical features of LCAT deficiency, and the impact of LCAT on cardiovascular disease from human studies.