Open AccessPro's and Con's of the early use of insulin in the management of type 2 diabetes: a clinical evaluation
Author(s) -
Mayer B. Davidson
Publication year - 2009
Publication title -
current opinion in endocrinology, diabetes and obesity./current opinion in endocrinology, diabetes and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.199
H-Index - 67
eISSN - 1752-2978
pISSN - 1752-296X
DOI - 10.1097/med.0b013e328322f92e
Subject(s) - insulin , medicine , diabetes mellitus , type 2 diabetes , drug , observational study , beta cell , endocrinology , pharmacology , islet
Recently, there have been increasing calls for insulin to be used as the initial treatment of type 2 diabetes, and if not then, soon after its onset. The underlying reason given is that insulin will slow down the apoptosis of pancreatic beta-cells, which is increased in type 2 diabetes. This review will examine the clinical evidence supporting this recommendation.