Open AccessArginases and arginine deficiency syndromes
Author(s) -
Sidney M. Morris
Publication year - 2012
Publication title -
current opinion in clinical nutrition and metabolic care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.21
H-Index - 111
eISSN - 1473-6519
pISSN - 1363-1950
DOI - 10.1097/mco.0b013e32834d1a08
Subject(s) - arginase , arginine , context (archaeology) , nitric oxide , medicine , hemolysis , ornithine , citrulline , immunology , biology , biochemistry , amino acid , paleontology
Many physiologic and pathophysiologic processes are modulated by arginine availability, which can be regulated by arginase. An understanding of the conditions that result in elevated arginase activity as well as the consequences of arginine deficiency is essential for design of effective nutritional support for disease. This review will emphasize recent findings regarding effects of plasma arginase and arginine deficiencies in disease.