Open AccessMitochondrial Protection by Resveratrol
Author(s) -
Zoltán Ungvári,
William E. Sonntag,
Rafael de Cabo,
Joseph A. Baur,
Anna Csiszár
Publication year - 2011
Publication title -
exercise and sport sciences reviews
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1097/jes.0b013e3182141f80
Subject(s) - resveratrol , chemistry , biology , pharmacology
Mitochondrial dysfunction and oxidative stress are thought to play important roles in mammalian aging. Resveratrol is a plant-derived polyphenol that exerts diverse antiaging activities, mimicking some of the molecular and functional effects of dietary restriction. This review focuses on the molecular mechanisms underlying the mitochondrial protective effects of resveratrol, which could be exploited for the prevention or amelioration of age-related diseases in the elderly.