
A Role for Myokines in Muscle-Bone Interactions
Author(s) -
Mark W. Hamrick
Publication year - 2011
Publication title -
exercise and sport sciences reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1097/jes.0b013e318201f601
Subject(s) - myokine , secretion , skeletal muscle , muscle mass , bone mass , endocrinology , medicine , biology , osteoporosis
This review presents the hypothesis that muscle is a source of secreted factors (myokines) that can influence bone mass in both positive and negative ways. Growth factor secretion by muscle may therefore be one pathway through which mechanical signals are transduced biologically.