Open AccessNeutrophil CD64 as a Diagnostic Marker in Neonatal Sepsis
Author(s) -
Iris Streimish,
Matthew J. Bizzarro,
Veronika Northrup,
Chao Wang,
Sara Renna,
Nancy Koval,
Fangyong Li,
Richard A. Ehrenkranz,
Henry M. Rinder,
Vineet Bhandari
Publication year - 2012
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0b013e318256fb07
Subject(s) - cd64 , medicine , sepsis , neonatal sepsis , predictive value , gastroenterology , immunology , receptor
We assessed neutrophil CD64 as a diagnostic marker for neonatal sepsis. For early-onset sepsis, the CD64 index with a cut-point value of 2.38 had sensitivity, specificity and negative predictive values of 100%, 68% and 100%, respectively. For late-onset sepsis, the respective values were 3.62, 75%, 77% and 96%. Neutrophil CD64 index can be incorporated as a valuable marker for excluding neonatal sepsis.