
Viral Load and Acute Otitis Media Development After Human Metapneumovirus Upper Respiratory Tract Infection
Author(s) -
JohanoksoKoivisto,
Richard B. Pyles,
Aaron L. Miller,
Janak A. Patel,
Michael J. Loeffelholz,
Tasnee Chonmaitree
Publication year - 2012
Publication title -
the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0b013e3182539d92
Subject(s) - human metapneumovirus , acute otitis media , medicine , respiratory tract infections , otitis , respiratory tract , virology , viral load , upper respiratory tract infection , lower respiratory tract infection , respiratory system , virus , immunology , surgery
The role of human metapneumovirus (hMPV) in acute otitis media complicating upper respiratory tract infection (URI) was studied. Nasopharyngeal specimens from 700 URI episodes in 200 children were evaluated; 47 (7%) were positive for hMPV, 25 (3.6%) with hMPV as the only virus. Overall, 24% of URI episodes with hMPV only were complicated by acute otitis media, which was the lowest rate compared with other respiratory viruses. hMPV viral load was significantly higher in children with fever, but there was no difference in viral load in children with hMPV-positive URI with or without acute otitis media complication.
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