Open AccessEvolution of the Epidemiology of Pneumococcal Disease Among Utah Children Through the Vaccine Era
Author(s) -
Krow Ampofo,
Andrew T. Pavia,
Chris Stockmann,
Anne J. Blaschke,
HsinYi Weng,
Kent Korgenski,
Judy A. Daly,
Carrie L. Byington
Publication year - 2011
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0b013e318232ee3e
Subject(s) - epidemiology , pneumococcal disease , pneumococcal vaccine , medicine , pediatrics , streptococcus pneumoniae , biology , microbiology and biotechnology , antibiotics
From 1996 to 2009, we analyzed changes in pneumococcal disease (PD) in Utah children aged <18 years using International Classification of Diseases, ninth revision coded hospital discharges. We observed a sustained decrease in the incidence of PD among children <5 years in 2001-2004 (-36%) and 2005-2009 (-34%) compared with 1996-2000 (pre-7-valent pneumococcal conjugate vaccine). Decreases were primarily in bacteremia, uncomplicated pneumonia, and meningitis. In contrast, significant increases in complicated pneumonia/empyema were noted in children <5 years (+95% and +85%) and 5 to 17 years (+2% and +70%). Despite decreases in PD among Utah children, complicated pneumonia/empyema has increased during the 7-valent pneumococcal conjugate vaccine era.