Open AccessCharacteristics of Vaccine Failures in a Randomized Placebo-controlled Trial of Inactivated Influenza Vaccine in Children
Author(s) -
Sophia Ng,
Michael Y. Ni,
Vicky J. Fang,
Dennis K. M. Ip,
KwokHung Chan,
Gabriel M. Leung,
Malik Peiris,
Benjamin J. Cowling
Publication year - 2014
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000000064
Subject(s) - viral shedding , vaccination , medicine , virology , influenza vaccine , placebo , inactivated vaccine , viral load , vaccine efficacy , randomized controlled trial , immunology , vaccine failure , virus , live attenuated influenza vaccine , trivalent influenza vaccine , clinical trial , antibody , measles , alternative medicine , pathology
Infections occurring among vaccinated persons (vaccine failures) are known to occur in vaccines with imperfect efficacy. Failures among vaccinated children who were infected with vaccine-matched influenza B virus strain have not been adequately characterized.