Open AccessFront‐line treatment of multiple myeloma
Author(s) -
Cavo Michele,
Tacchetti Paola,
Zamagni Elena
Publication year - 2019
Publication title -
hemasphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 11
ISSN - 2572-9241
DOI - 10.1097/hs9.0000000000000242
Subject(s) - front line , multiple myeloma , front (military) , line (geometry) , medicine , geography , mathematics , meteorology , geometry , archaeology
Incorporation of novel agents into the treatment paradigms for fit patients with newly diagnosed multiple myeloma has led to a remarkable increase in the rates of complete response and minimal residual disease negative status, ultimately translating into near tripling of median overall survival of this disease. In frail individuals who cannot tolerate multi-drug combinations treatment goals include improvement in the quality of life and avoidance of early treatment discontinuation due to drug toxicities.