A formal risk-benefit framework for genomic tests: Facilitating the appropriate translation of genomics into clinical practice | Zendy

David L. Veenstra | Zendy; Joshua A. Roth | Zendy; Louis P. Garrison | Zendy; Scott D. Ramsey | Zendy; Wylie Burke | Zendy

Open Access

A formal risk-benefit framework for genomic tests: Facilitating the appropriate translation of genomics into clinical practice

Author(s) -

David L. Veenstra,

Joshua A. Roth,

Louis P. Garrison,

Scott D. Ramsey,

Wylie Burke

Publication year - 2010

Publication title -

genetics in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.509

H-Index - 128

eISSN - 1530-0366

pISSN - 1098-3600

DOI - 10.1097/gim.0b013e3181eff533

Subject(s) - life expectancy , stakeholder , health care , risk analysis (engineering) , risk assessment , medicine , computer science , environmental health , population , public relations , computer security , political science , economics , economic growth

Evaluation of genomic tests is often challenging because of the lack of direct evidence of clinical benefit compared with usual care and unclear evidence requirements. To address these issues, this study presents a risk-benefit framework for assessing the health-related utility of genomic tests.

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