Genetic risk factors for type 2 diabetes mellitus and response to sulfonylurea treatment | Zendy

Jesse J. Swen | Zendy; HenkJan Guchelaar | Zendy; Renée Baak-Pablo | Zendy; Willem JJ Assendelft | Zendy; Judith A.M. Wessels | Zendy

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Genetic risk factors for type 2 diabetes mellitus and response to sulfonylurea treatment

Author(s) -

Jesse J. Swen,

HenkJan Guchelaar,

Renée Baak-Pablo,

Willem JJ Assendelft,

Judith A.M. Wessels

Publication year - 2011

Publication title -

pharmacogenetics and genomics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.579

H-Index - 140

eISSN - 1744-6880

pISSN - 1744-6872

DOI - 10.1097/fpc.0b013e3283478173

Subject(s) - sulfonylurea , pharmacogenetics , medicine , type 2 diabetes mellitus , diabetes mellitus , bioinformatics , pharmacology , biology , genetics , endocrinology , gene , genotype

After the identification of type 2 diabetes mellitus (T2DM) risk alleles from genome-wide association studies, models have been developed to identify subjects at high risk to develop T2DM. We hypothesize that a panel of 20 repeatedly associated T2DM risk alleles influences response to sulfonylureas (SUs).

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