Open AccessDoes Antidepressant Use Attenuate the Risk of a Major Depressive Episode in Pregnancy?
Author(s) -
Kimberly A. Yonkers,
Nathan Gotman,
Megan V. Smith,
Ariadna Forray,
Kathleen Belanger,
Wendy L. Brunetto,
Haiqun Lin,
Ronald T. Burkman,
Carolyn M. Zelop,
Charles J. Lockwood
Publication year - 2011
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/ede.0b013e3182306847
Subject(s) - discontinuation , antidepressant , medicine , pregnancy , hazard ratio , major depressive disorder , major depressive episode , psychiatry , proportional hazards model , depression (economics) , obstetrics , confidence interval , anxiety , genetics , cognition , macroeconomics , economics , biology
Many women become pregnant while undergoing antidepressant treatment and are concerned about continuing antidepressant medication. However, antidepressant discontinuation may increase the risk of a new episode of major depressive disorder. We sought to estimate differences in the risk of developing a new major depressive episode among pregnant and postpartum women with recurrent illness who either did or did not use antidepressants.