Open AccessIs the central nervous system a reservoir of HIV-1?
Author(s) -
Lachlan Robert Gray,
Michael Roche,
Jacqueline K. Flynn,
Steve Wesselingh,
Paul R Gorry,
Melissa Churchill
Publication year - 2014
Publication title -
current opinion in hiv and aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 64
eISSN - 1746-6318
pISSN - 1746-630X
DOI - 10.1097/coh.0000000000000108
Subject(s) - viral load , central nervous system , viral replication , neurocognitive , microglia , immunology , epigenetics , medicine , antiretroviral therapy , biology , human immunodeficiency virus (hiv) , inflammation , virology , virus , neuroscience , genetics , cognition , gene
To summarize the evidence in the literature that supports the central nervous system (CNS) as a viral reservoir for HIV-1 and to prioritize future research efforts.