Open AccessChildhood Sjögren syndrome
Author(s) -
Scott M. Lieberman
Publication year - 2013
Publication title -
current opinion in rheumatology/current opinion in rheumatology, with evaluated medline
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.452
H-Index - 112
eISSN - 1080-8175
pISSN - 1040-8711
DOI - 10.1097/bor.0b013e328363ed23
Subject(s) - medicine , autoantibody , pathogenesis , rituximab , immunology , disease , autoimmune disease , autoimmunity , salivary gland , pathology , antibody
Sjögren syndrome is a chronic autoimmune disease affecting lacrimal and salivary glands that often is accompanied by extraglandular disease manifestations. Although common in adults, the prevalence and prognosis of childhood Sjögren syndrome are unknown, in part due to lack of child-specific diagnostic and classification criteria. This review discusses difficulties in diagnosing childhood Sjögren syndrome and highlights recent findings in Sjögren syndrome treatment and pathogenesis from studies in adults and animal models over the past 18 months.