Prognostic biomarkers in osteoarthritis | Zendy

Mukundan Attur | Zendy; Svetlana Krasnokutsky-Samuels | Zendy; Jonathan Samuels | Zendy; Steven B. Abramson | Zendy

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Prognostic biomarkers in osteoarthritis

Author(s) -

Mukundan Attur,

Svetlana Krasnokutsky-Samuels,

Jonathan Samuels,

Steven B. Abramson

Publication year - 2012

Publication title -

current opinion in rheumatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.452

H-Index - 112

eISSN - 1080-8175

pISSN - 1040-8711

DOI - 10.1097/bor.0b013e32835a9381

Subject(s) - osteoarthritis , medicine , cartilage , disease , biomarker , cartilage damage , bioinformatics , biomarker discovery , pathology , articular cartilage , oncology , proteomics , biology , alternative medicine , gene , anatomy , biochemistry

Identification of patients at risk for incident disease or disease progression in osteoarthritis remains challenging, as radiography is an insensitive reflection of molecular changes that presage cartilage and bone abnormalities. Thus there is a widely appreciated need for biochemical and imaging biomarkers. We describe recent developments with such biomarkers to identify osteoarthritis patients who are at risk for disease progression.

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