Aversive and Reinforcing Opioid Effects | Zendy

Martin S. Angst | Zendy; Laura C. Lazzeroni | Zendy; Nicholas G. Phillips | Zendy; David R. Drover | Zendy; Martha Tingle | Zendy; Amrita Ray | Zendy; Gary E. Swan | Zendy; James D. Clark | Zendy

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Aversive and Reinforcing Opioid Effects

Author(s) -

Martin S. Angst,

Laura C. Lazzeroni,

Nicholas G. Phillips,

David R. Drover,

Martha Tingle,

Amrita Ray,

Gary E. Swan,

James D. Clark

Publication year - 2012

Publication title -

anesthesiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.874

H-Index - 234

eISSN - 1528-1175

pISSN - 0003-3022

DOI - 10.1097/aln.0b013e31825a2a4e

Subject(s) - medicine , nausea , sedation , opioid , adverse effect , placebo , mood , alfentanil , sedative , anesthesia , psychiatry , fentanyl , alternative medicine , receptor , pathology

The clinical utility of opioids is limited by adverse drug effects including respiratory depression, sedation, nausea, and pruritus. In addition, abuse of prescription opioids is problematic. Gaining a better understanding of the genetic and environmental mechanisms contributing to an individual's susceptibility to adverse opioid effects is essential to identify patients at risk.

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