Metoprolol Reduces Cerebral Tissue Oxygen Tension after Acute Hemodilution in Rats | Zendy

Tenille E. Ragoonanan | Zendy; W. Scott Beattie | Zendy; C. David Mazer | Zendy; Albert K.Y. Tsui | Zendy; Howard LeongPoi | Zendy; David F. Wilson | Zendy; Gordon Tait | Zendy; Julie Yu | Zendy; Elaine Liu | Zendy; Melissa Noronha | Zendy; Neil D. Dattani | Zendy; Nicholas Mitsakakis | Zendy; Gregory M. T. Hare | Zendy

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Metoprolol Reduces Cerebral Tissue Oxygen Tension after Acute Hemodilution in Rats

Author(s) -

Tenille E. Ragoonanan,

W. Scott Beattie,

C. David Mazer,

Albert K.Y. Tsui,

Howard LeongPoi,

David F. Wilson,

Gordon Tait,

Julie Yu,

Elaine Liu,

Melissa Noronha,

Neil D. Dattani,

Nicholas Mitsakakis,

Gregory M. T. Hare

Publication year - 2009

Publication title -

anesthesiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.874

H-Index - 234

eISSN - 1528-1175

pISSN - 0003-3022

DOI - 10.1097/aln.0b013e3181b87f0e

Subject(s) - medicine , erythropoietin , cardiac output , cerebral blood flow , metoprolol , anesthesia , oxygen tension , blockade , stroke volume , renal blood flow , hypoxia (environmental) , heart rate , endocrinology , hemodynamics , blood pressure , oxygen , chemistry , receptor , organic chemistry

Perioperative beta-blockade and anemia are independent predictors of increased stroke and mortality by undefined mechanisms. This study investigated the effect of beta-blockade on cerebral tissue oxygen delivery in an experimental model of blood loss and fluid resuscitation (hemodilution).

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