Open AccessEffects of Immunosuppressive Agents on Magnesium Metabolism Early after Allogeneic Hematopoietic Stem Cell Transplantation
Author(s) -
Yoshinobu Aisa,
Takehiko Mori,
Tomonori Nakazato,
Takayuki Shioiri,
Rie Yamazaki,
Yasuo Ikeda,
Shinichiro Okamoto
Publication year - 2005
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/01.tp.0000174340.40585.d4
Subject(s) - tacrolimus , calcineurin , hypomagnesemia , medicine , transplantation , urinary system , hematopoietic stem cell transplantation , excretion , ciclosporin , endocrinology , gastroenterology , pharmacology , urology , magnesium , chemistry , organic chemistry
The calcineurin inhibitors, cyclosporine A (CSA) and tacrolimus, cause hypomagnesemia by suppressing reabsorption of magnesium (Mg) from renal tubules. To assess whether the effect on Mg metabolism after allogeneic hematopoietic stem cell transplantation (HSCT) differs among calcineurin inhibitors, we prospectively evaluated the Mg metabolism in recipients of allogeneic HSCT who received CSA or tacrolimus