Abstract 39: Characterization And Functional Analysis Of Skin Dendritic Cell Subpopulations In Vascularized Composite Allotransplantation | Zendy

Wensheng Zhang | Zendy; Chiaki Komatsu | Zendy; Jiaqing Wu | Zendy; Firuz Feturi | Zendy; Jeff Walsh | Zendy; Jingjing Li | Zendy; Lin He | Zendy; Maxine R. Miller | Zendy; Alicia R. Mathers | Zendy; Angus W. Thomson | Zendy; Vijay S. Gorantla | Zendy; Kia M. Washington | Zendy; Mario G. Solari | Zendy

Open Access

Abstract 39: Characterization And Functional Analysis Of Skin Dendritic Cell Subpopulations In Vascularized Composite Allotransplantation

Author(s) -

Wensheng Zhang,

Chiaki Komatsu,

Jiaqing Wu,

Firuz Feturi,

Jeff Walsh,

Jingjing Li,

Lin He,

Maxine R. Miller,

Alicia R. Mathers,

Angus W. Thomson,

Vijay S. Gorantla,

Kia M. Washington,

Mario G. Solari

Publication year - 2018

Publication title -

plastic and reconstructive surgery global open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.759

H-Index - 28

ISSN - 2169-7574

DOI - 10.1097/01.gox.0000533904.72280.58

Subject(s) - immune system , allotransplantation , immunosuppression , alloimmunity , dendritic cell , immunology , flow cytometry , medicine , mixed lymphocyte reaction , transplantation , t cell

was present despite the presence of retinal blood flow as confirmed by OCT. Allografts may be less vascularized than syngeneic whole eye transplantations. In addition, histopathology reveals some inflammation and neovascularization to the cornea and central degeneration of the retina. These findings serve as targets for future, therapies, improvements and investigation. Future studies of systemic and local immunosuppressive therapies are necessary to support the structural and functional success of whole-eye allotransplantation.

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