Open AccessA genome scan in 260 inflammatory bowel disease‐affected relative pairs
Author(s) -
Barmada M. Michael,
Brant Steven R.,
Nicolae Dan L.,
Achkar JeanPaul,
Panhuysen Carolien I.,
Bayless Theodore M.,
Cho Judy H.,
Duerr Richard H.
Publication year - 2004
Publication title -
inflammatory bowel diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.932
H-Index - 146
eISSN - 1536-4844
pISSN - 1078-0998
DOI - 10.1097/00054725-200401000-00002
Subject(s) - genome , inflammatory bowel disease , linkage (software) , genome scan , disease , medicine , genetic linkage , genetics , computational biology , biology , gene , microsatellite , allele
We report the results of a new genome scan in 260 IBD‐affected relative pairs from 139 families that we have recruited since our previous IBD genome scans were performed. The goal of our study was to determine whether we could extend the linkage evidence in any of the more than 20 regions with nominal evidence for linkage to IBD in previous individual genome scans in order to prioritize regions for further study.