Open AccessSevere, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy
Author(s) -
Dianne Langford,
Scott Letendre,
Thomas D. Marcotte,
Ronald J. Ellis,
J. Allen McCutchan,
Igor Grant,
Margaret Mallory,
Lawrence A. Hansen,
Sarah Archibald,
Terry L. Jernigan,
Eliezer Masliah
Publication year - 2002
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/00002030-200205030-00008
Subject(s) - progressive multifocal leukoencephalopathy , astrogliosis , jc virus , leukoencephalopathy , medicine , pathology , brain biopsy , immunology , multiple sclerosis , biopsy , central nervous system , disease
To describe a severe form of demyelinating HIV-associated leukoencephalopathy in AIDS patients failing highly active antiretroviral therapy (HAART), its relationship to clinical and neuroimaging findings, and suggest hypotheses regarding pathogenesis.