Open AccessPneumocystis carinii mutations associated with sulfa and sulfone prophylaxis failures in AIDS patients
Author(s) -
Powel Kazanjian,
Amy Locke,
Paul A. Hossler,
Brian R. Lane,
Marilyn S. Bartlett,
James W. Smith,
Mark Can,
Steven R. Meshnick
Publication year - 1998
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/00002030-199808000-00009
Subject(s) - pneumocystis carinii , sulfone , dihydropteroate synthase , dhps , medicine , pneumonia , virology , biology , immunology , pyrimethamine , chemistry , malaria , polymer chemistry , plasmodium falciparum , pneumocystis jirovecii
Failures of prophylaxis against Pneumocystis carinii pneumonia (PCP) in AIDS patients do occur, but no evidence for drug resistance has yet been presented.