Immunopurified Anti-Müllerian Hormone does not Inhibit Spontaneous Resumption of Meiosis in Vitro of Rat Oocytes1 | Zendy

A. Tsafriri | Zendy; J. Y. Picard | Zendy; Nathalie Josso | Zendy

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Immunopurified Anti-Müllerian Hormone does not Inhibit Spontaneous Resumption of Meiosis in Vitro of Rat Oocytes1

Author(s) -

A. Tsafriri,

J. Y. Picard,

Nathalie Josso

Publication year - 1988

Publication title -

biology of reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.366

H-Index - 180

eISSN - 1529-7268

pISSN - 0006-3363

DOI - 10.1095/biolreprod38.2.481

Subject(s) - biology , anti müllerian hormone , in vitro , meiosis , hormone , microbiology and biotechnology , endocrinology , medicine , andrology , genetics , gene

The ability of immunopurified, biologically potent anti-Müllerian hormone (AMH) to inhibit the spontaneous resumption of meiosis of rat oocytes was tested in vitro. Two different batches of AMH in the range of 0.75-9.0 micrograms/protein did not suppress the spontaneous resumption of meiosis. Neither did AMH (6 micrograms/ml) induce meiotic resumption of follicle-enclosed oocytes in culture. It is concluded, therefore, that AMH has no oocyte meiosis-inhibiting activity.

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