In Vivo Effects of Follicle-stimulating Hormone on Testicular Macrophages | Zendy

James B. Yee | Zendy; James C. Hutson | Zendy

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In Vivo Effects of Follicle-stimulating Hormone on Testicular Macrophages

Author(s) -

James B. Yee,

James C. Hutson

Publication year - 1985

Publication title -

biology of reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.366

H-Index - 180

eISSN - 1529-7268

pISSN - 0006-3363

DOI - 10.1095/biolreprod32.4.880

Subject(s) - biology , luteinizing hormone , hormone , uridine , in vivo , medicine , follicle stimulating hormone , endocrinology , amino acid , rna , biochemistry , microbiology and biotechnology , gene

The effect of an intraperitoneal injection of various hormones on the incorporation of amino acids and uridine into acid-precipitable material by subsequently isolated testicular macrophages was investigated. It was found that treatment with follicle-stimulating hormone (FSH), but not luteinizing hormone (LH) or insulin, significantly increased incorporation of amino acids into secreted (but not cellular) protein and uridine incorporation into cellular RNA in a dose-dependent manner. Maximal responsiveness was observed at a dose of 50 micrograms of the hormone. These studies demonstrate that FSH has an action on testicular macrophages in vivo.

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