Open AccessExpression Profiles of Genes Encoded by the Supernumerary Chromosome Controlling AM-Toxin Biosynthesis and Pathogenicity in the Apple Pathotype of Alternaria alternata
Author(s) -
Yoshiaki Harimoto,
Rieko Hatta,
Motoichiro Kodama,
Mikihiro Yamamoto,
Hiroshi Otani,
Takashi Tsuge
Publication year - 2007
Publication title -
molecular plant-microbe interactions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.565
H-Index - 153
eISSN - 1943-7706
pISSN - 0894-0282
DOI - 10.1094/mpmi-20-12-1463
Subject(s) - alternaria alternata , biology , supernumerary , gene , pathogenicity , genetics , chromosome , toxin , microbiology and biotechnology , botany , anatomy
The apple pathotype of Alternaria alternata produces host-specific AM-toxin and causes Alternaria blotch of apple. Previously, we cloned two genes, AMT1 and AMT2, required for AM-toxin biosynthesis and found that these genes are encoded by small, supernumerary chromosomes of 10-fold) in AM-toxin–producing cultures. Two of the upregulated genes were newly identified to be involved in AM-toxin biosynthesis by the gene disruption experiments and were named AMT3 and AMT4. Thus, the genes upregulated in AM-toxin–producing cultures contain ideal candidates for novel AM-toxin biosynthetic genes.