Open AccessThree-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening
Author(s) -
Sreenivasa Ramaiahgari,
Suramya Waidyanatha,
Darlene Dixon,
Michael J. DeVito,
Richard S. Paules,
Stephen Ferguson
Publication year - 2017
Publication title -
toxicological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.352
H-Index - 183
eISSN - 1096-6080
pISSN - 1096-0929
DOI - 10.1093/toxsci/kfx194
Subject(s) - spheroid , hepatocyte , xenobiotic , toxicity , drug metabolism , metabolism , liver toxicity , chemistry , pharmacology , liver metabolism , microbiology and biotechnology , biology , biochemistry , in vitro , enzyme , organic chemistry
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