Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform
Author(s) -
Roberta Visone,
Ferran Lozano-Juan,
Simona Marzorati,
Massimo W. Rivolta,
Enrico Pesenti,
Alberto Redaelli,
Roberto Sassi,
Marco Rasponi,
Paola Occhetta
Publication year - 2022
Publication title -
toxicological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.352
H-Index - 183
eISSN - 1096-6080
pISSN - 1096-0929
DOI - 10.1093/toxsci/kfac108
Subject(s) - cardiotoxicity , medicine , induced pluripotent stem cell , qt interval , safety pharmacology , pharmacology , drug , electrophysiology , human heart , cardiac electrophysiology , herg , drug development , cardiology , potassium channel , toxicity , chemistry , biochemistry , embryonic stem cell , gene
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