Open AccessClozapine Induces an Acute Proinflammatory Response That Is Attenuated by Inhibition of Inflammasome Signaling: Implications for Idiosyncratic Drug-Induced Agranulocytosis
Author(s) -
Samantha Christine Sernoskie,
Alexandra R. Lobach,
Ryuji Kato,
Alison Jee,
Joseph Kyle Weston,
Jack Uetrecht
Publication year - 2021
Publication title -
toxicological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.352
H-Index - 183
eISSN - 1096-6080
pISSN - 1096-0929
DOI - 10.1093/toxsci/kfab154
Subject(s) - inflammasome , clozapine , pharmacology , proinflammatory cytokine , medicine , caspase 1 , anakinra , inflammation , immunology , schizophrenia (object oriented programming) , disease , psychiatry
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