Open AccessAn arrayed CRISPR screen reveals Myc depletion to increase productivity of difficult-to-express complex antibodies in CHO cells
Author(s) -
Niels Bauer,
Benedikt Oswald,
Maximilian Eiche,
Lisa Schiller,
Emma Langguth,
Christian Schantz,
Andrea Osterlehner,
Amy Shen,
Shahram Misaghi,
Julian Stingele,
Simon Ausländer
Publication year - 2022
Publication title -
synthetic biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.769
H-Index - 8
ISSN - 2397-7000
DOI - 10.1093/synbio/ysac026
Subject(s) - crispr , chinese hamster ovary cell , cas9 , antibody , biology , monoclonal antibody , computational biology , microbiology and biotechnology , cell culture , gene , immunology , genetics
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