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Building Biofoundry India: challenges and path forward
Author(s) -
Binay Panda,
Pawan K. Dhar
Publication year - 2021
Publication title -
synthetic biology
Language(s) - English
Resource type - Journals
ISSN - 2397-7000
DOI - 10.1093/synbio/ysab015
Subject(s) - biomanufacturing , workflow , modular design , computer science , key (lock) , path (computing) , automation , data science , systems engineering , software engineering , engineering , computer security , microbiology and biotechnology , mechanical engineering , database , biology , programming language , operating system
Biofoundry is a place where biomanufacturing meets automation. The highly modular structure of a biofoundry helps accelerate the design–build–test–learn workflow to deliver products fast and in a streamlined fashion. In this perspective, we describe our efforts to build Biofoundry India, where we see the facility add a substantial value in supporting research, innovation and entrepreneurship. We describe three key areas of our focus, harnessing the potential of non-expressing parts of the sequenced genomes, using deep learning in pathway reconstruction and synthesising enzymes and metabolites. Toward the end, we describe specific challenges in building such facility in India and the path to mitigate some of those working with the other biofoundries worldwide.

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