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Periodic Limb Movements and White Matter Hyperintensities in First-Ever Minor Stroke or High-Risk Transient Ischemic Attack
Author(s) -
Mark I. Boulos,
Brian J. Murray,
Ryan T. Muir,
Fuqiang Gao,
Gregory M. Szilagyi,
Menal Huroy,
Alexander Kiss,
Arthur S. Walters,
Sandra E. Black,
Andrew Lim,
Richard H. Swartz
Publication year - 2016
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.1093/sleep/zsw080
Subject(s) - stroke (engine) , medicine , cardiology , hyperintensity , leukoaraiosis , severity of illness , risk factor , physical therapy , disease , magnetic resonance imaging , dementia , engineering , radiology , mechanical engineering
Emerging evidence suggests that periodic limb movements (PLMs) may contribute to the development of cerebrovascular disease. White matter hyperintensities (WMHs), a widely accepted biomarker for cerebral small vessel disease, are associated with incident stroke and death. We evaluated the association between increased PLM indices and WMH burden in patients presenting with stroke or transient ischemic attack (TIA), while controlling for vascular risk factors and stroke severity.

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