A New Animal Model of Obstructive Sleep Apnea Responding to Continuous Positive Airway Pressure | Zendy

PierreCharles Neuzeret | Zendy; F. Gormand | Zendy; Philippe Reix | Zendy; Sandrine Parrot | Zendy; JeanPierre Sastre | Zendy; Colette Buda | Zendy; G. Guidon | Zendy; Kazuya Sakai | Zendy; JianSheng Lin | Zendy

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A New Animal Model of Obstructive Sleep Apnea Responding to Continuous Positive Airway Pressure

Author(s) -

PierreCharles Neuzeret,

F. Gormand,

Philippe Reix,

Sandrine Parrot,

JeanPierre Sastre,

Colette Buda,

G. Guidon,

Kazuya Sakai,

JianSheng Lin

Publication year - 2011

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.1093/sleep/34.4.541

Subject(s) - obstructive sleep apnea , continuous positive airway pressure , medicine , sleep (system call) , sleep apnea , airway , apnea , anesthesia , cardiology , computer science , operating system

An improved animal model of obstructive sleep apnea (OSA) is needed for the development of effective pharmacotherapies. In humans, flexion of the neck and a supine position, two main pathogenic factors during human sleep, are associated with substantially greater OSA severity. We postulated that these two factors might generate OSA in animals.

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