Neuropeptide B Induces Slow Wave Sleep in Mice | Zendy

Noriko Hirashima | Zendy; Tomomi Tsunematsu | Zendy; Kanako Ichiki | Zendy; Hirokazu Tanaka | Zendy; Thomas S. Kilduff | Zendy; Akihiro Yamanaka | Zendy

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Neuropeptide B Induces Slow Wave Sleep in Mice

Author(s) -

Noriko Hirashima,

Tomomi Tsunematsu,

Kanako Ichiki,

Hirokazu Tanaka,

Thomas S. Kilduff,

Akihiro Yamanaka

Publication year - 2011

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.1093/sleep/34.1.31

Subject(s) - neuropeptide , g protein coupled receptor , neuropeptide y receptor , receptor , endogeny , endocrinology , biology , medicine , sleep (system call) , neuroscience , computer science , operating system

Neuropeptide B (NPB) and neuropeptide W (NPW) are two recently identified neuropeptides that act as endogenous ligands to orphan G protein coupled receptors, GPR7 and GPR8. In rodents, the GPR8 ortholog is absent and both NPB and NPW function exclusively through GPR7. Although NPB and NPW are implicated in the regulation of feeding behavior, endocrine function, and pain sensation, their physiological role is incompletely understood.

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