Changes in Components of Energy Regulation in Mouse Cortex with Increases in Wakefulness | Zendy

Eleikonova | Zendy; Nirinjini Naidoo | Zendy; Lin Zhang | Zendy; Micah Romer | Zendy; Jacqueline Cater | Zendy; Matthew T. Scharf | Zendy; Raymond J. Galante | Zendy; Allan I Pack | Zendy

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Changes in Components of Energy Regulation in Mouse Cortex with Increases in Wakefulness

Author(s) -

Eleikonova,

Nirinjini Naidoo,

Lin Zhang,

Micah Romer,

Jacqueline Cater,

Matthew T. Scharf,

Raymond J. Galante,

Allan I Pack

Publication year - 2010

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.1093/sleep/33.7.889

Subject(s) - wakefulness , sleep deprivation , neuroscience , sleep (system call) , mechanism (biology) , cortex (anatomy) , psychology , electroencephalography , circadian rhythm , computer science , physics , quantum mechanics , operating system

Increases in ATP production machinery have been described in brain after 3 h of sleep deprivation. Whether this is sustained with longer durations of extended wakefulness is unknown. We hypothesized that energy depletion could be a mechanism leading to difficulty maintaining wakefulness and assessed changes in components of the electron transport chain.

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