Central Sleep Apnea Indicates Autonomic Dysfunction in Asymptomatic Carotid Stenosis: A Potential Marker of Cerebrovascular and Cardiovascular Risk | Zendy

Sven Rupprecht | Zendy; Dirk Hoyer | Zendy; Georg Hagemann | Zendy; Otto W. Witte | Zendy; Matthias Schwab | Zendy

Open Access

Central Sleep Apnea Indicates Autonomic Dysfunction in Asymptomatic Carotid Stenosis: A Potential Marker of Cerebrovascular and Cardiovascular Risk

Author(s) -

Sven Rupprecht,

Dirk Hoyer,

Georg Hagemann,

Otto W. Witte,

Matthias Schwab

Publication year - 2010

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.1093/sleep/33.3.327

Subject(s) - baroreceptor , cardiology , medicine , stenosis , asymptomatic , sleep apnea , obstructive sleep apnea , anesthesia , heart rate , blood pressure

Arteriosclerosis related stenosis in the carotid bulb causes autonomic imbalance, likely due to carotid chemoreceptor and baroreceptor dysfunction. The latter are associated with increased cerebrovascular and cardiovascular mortality. Chemoreceptor and baroreceptor dysfunction is also involved in the origin of central sleep apnea syndrome (CSA) in different clinical entities. We hypothesized that CSA is associated with stenosis of the internal carotid artery (ICA). The mechanism of this association is an autonomic imbalance induced by stenosis-mediated chemoreceptor and baroreceptor dysfunction.

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