Inter-Individual Differences In Habitual Sleep Timing and Entrained Phase of Endogenous Circadian Rhythms of BMAL1, PER2 and PER3 mRNA in Human Leukocytes | Zendy

Simon Archer | Zendy; Antoine Viola | Zendy; Vanessa Kyriakopoulou | Zendy; Malcolm von Schantz | Zendy; DerkJan Dijk | Zendy

Open Access

Inter-Individual Differences In Habitual Sleep Timing and Entrained Phase of Endogenous Circadian Rhythms of BMAL1, PER2 and PER3 mRNA in Human Leukocytes

Author(s) -

Simon Archer,

Antoine Viola,

Vanessa Kyriakopoulou,

Malcolm von Schantz,

DerkJan Dijk

Publication year - 2008

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.1093/sleep/31.5.608

Subject(s) - per2 , circadian rhythm , actigraphy , endocrinology , medicine , melatonin , clock , circadian clock , free running sleep , dark therapy , light effects on circadian rhythm , biology , endogeny , psychology

Individual sleep timing differs and is governed partly by circadian oscillators, which may be assessed by hormonal markers, or by clock gene expression. Clock gene expression oscillates in peripheral tissues, including leukocytes. The study objective was to determine whether the endogenous phase of these rhythms, assessed in the absence of the sleep-wake and light-dark cycle, correlates with habitual sleep-wake timing.

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