Relationship Between Rem Density, Duty Cycle, and Obstructive Sleep Apnea in Children

The pattern and distribution of rapid eye movement (REM) sleep changes during development, yet there have been few studies of REM density in children. Although children with obstructive apnea syndrome (OSAS) obstruct primarily during REM sleep, the relationship between REM density and obstructive apnea has not been established for this population. We hypothesized that (i) REM density and REM cycle duration increases over the course of the night in children, (ii) the duty cycle (inspiratory time divided by respiratory cycle time) increases over the course of the night in children with suspected OSAS, and (iii) the increase in REM density over the course of the night is associated with increased severity of obstructive apnea.