Proton Magnetic Resonance Spectroscopy Study of Brain Metabolism in Obstructive Sleep Apnoea Syndrome before and after Continuous Positive Airway Pressure Treatment
Author(s) -
Caterina To,
Roberto Vetrugno,
Raffaele Lodi,
R. Gallassi,
Federica Provini,
Stefano Iotti,
Giuseppe Plazzi,
Pasquale Montagna,
E Lugaresi,
Bruno Barbiroli
Publication year - 2007
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.1093/sleep/30.3.305
Subject(s) - medicine , continuous positive airway pressure , excessive daytime sleepiness , sleep (system call) , obstructive sleep apnea , anesthesia , cardiology , pathogenesis , sleep disorder , cognition , psychiatry , computer science , operating system
Obstructive sleep apnoea syndrome (OSAS) causes sleep related oxygen desaturation, excessive daytime sleepiness (EDS), and cognitive impairment. The role of hypoxic brain damage, sleep fragmentation, and the associated comorbidities (hypertension, vascular disorders) in the pathogenesis of cognitive deficits remains controversial. The aim of this study was to evaluate the cerebral metabolism of OSAS patients in vivo before and after CPAP treatment.
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