Acute Intravenous Administration of Morphine Perturbs Sleep Architecture in Healthy Pain-Free Young Adults: a Preliminary Study | Zendy

Isabelle Raymond Shaw | Zendy; Gilles Lavigne | Zendy; Pierre Mayer | Zendy; Ma Choinière | Zendy

Open Access

Acute Intravenous Administration of Morphine Perturbs Sleep Architecture in Healthy Pain-Free Young Adults: a Preliminary Study

Author(s) -

Isabelle Raymond Shaw,

Gilles Lavigne,

Pierre Mayer,

Ma Choinière

Publication year - 2005

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.1093/sleep/28.6.677

Subject(s) - medicine , anesthesia , slow wave sleep , sleep (system call) , morphine , polysomnography , opioid , placebo , sleep onset , electroencephalography , apnea , insomnia , receptor , alternative medicine , pathology , psychiatry , computer science , operating system

Pain is a leading cause of sleep disturbances in medical illness. Providing effective analgesia is considered an important intervention to reduce these sleep disturbances. Opioids remain the treatment of choice to relieve postoperative pain in hospitalized patients. However, their effects on sleep in pain patients or normal subjects remain unclear, as previous studies have been conducted mainly with former opioid addicts. The purpose of this investigation was to evaluate and describe the effects of acute clinical doses of morphine on sleep in healthy pain-free subjects.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research