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To assess the efficacy of added carbon dioxide as adjunctive therapy to positive airway pressure-refractory mixed obstructive and central sleep-disordered breathing, using a prototype device-the positive airway pressure gas modulator.

sleep

Low-Concentration Carbon Dioxide is an Effective Adjunct to Positive Airway Pressure in the Treatment of Refractory Mixed Central and Obstructive Sleep-Disordered Breathing