Differences in Activity of Cytochrome C Oxidase in Brain Between Sleep and Wakefulness | Zendy

Eleikonova | Zendy; Camasamudram Vijayasarathy | Zendy; Lin Zhang | Zendy; Jacqueline Cater | Zendy; Raymond J. Galante | Zendy; Stephen E. Ward | Zendy; Narayan G. Avadhani | Zendy; Allan I Pack | Zendy

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Differences in Activity of Cytochrome C Oxidase in Brain Between Sleep and Wakefulness

Author(s) -

Eleikonova,

Camasamudram Vijayasarathy,

Lin Zhang,

Jacqueline Cater,

Raymond J. Galante,

Stephen E. Ward,

Narayan G. Avadhani,

Allan I Pack

Publication year - 2005

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.1093/sleep/28.1.21

Subject(s) - cytochrome c oxidase , wakefulness , sleep deprivation , endocrinology , circadian rhythm , medicine , sleep (system call) , enzyme assay , enzyme , biology , neuroscience , biochemistry , electroencephalography , computer science , operating system

Increased mRNA level of subunit 1 cytochrome c oxidase (COXI) during wakefulness and after short-term sleep deprivation has been described in brain. We hypothesized that this might contribute to increased activity of cytochrome oxidase (COX) enzyme during wakefulness, as part of the mechanisms to provide sufficient amounts of adenosine triphosphate to meet increased neuronal energy demands.

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