Open AccessIncreased Muscle Activity During Rapid Eye Movement Sleep Correlates with Decrease of Striatal Presynaptic Dopamine Transporters. IPT and IBZM SPECT Imaging in Subclinical and Clinically Manifest Idiopathic REM Sleep Behavior Disorder, Parkinson's Disease, and Controls
Author(s) -
Ilonka Eisensehr,
R. Linke,
Klaus Tatsch,
Bita Kharraz,
Josef F Gildehaus,
Christian T Wetter,
Claudia Trenkwalder,
Johannes Schwarz,
Soheyl Noachtar
Publication year - 2003
Publication title -
sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.222
H-Index - 207
eISSN - 1550-9109
pISSN - 0161-8105
DOI - 10.1093/sleep/26.5.507
Subject(s) - subclinical infection , dopamine transporter , dopamine , rapid eye movement sleep , medicine , rem sleep behavior disorder , parkinson's disease , endocrinology , psychology , dopaminergic , gastroenterology , neuroscience , disease , eye movement
Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by complex behavior during REM sleep. The etiology of this disorder is still unknown, but a recent study showed that RBD precedes symptoms of Parkinson disease (PD) by several years, and in a previous study, we found reduced striatal dopamine transporters in idiopathic clinically manifest RBD.
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