Carbamazepine as a Treatment for Cataplexy | Zendy

Bradley V. Vaughn | Zendy; O’Neill F. D’Cruz | Zendy

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Carbamazepine as a Treatment for Cataplexy

Author(s) -

Bradley V. Vaughn,

O’Neill F. D’Cruz

Publication year - 1996

Publication title -

sleep

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.222

H-Index - 207

eISSN - 1550-9109

pISSN - 0161-8105

DOI - 10.1093/sleep/19.2.101

Subject(s) - cataplexy , narcolepsy , sleep paralysis , sertraline , anesthesia , polysomnogram , psychology , choreiform movement , polysomnography , multiple sleep latency test , medicine , carbamazepine , sleep disorder , excessive daytime sleepiness , modafinil , psychiatry , insomnia , epilepsy , dyskinesia , apnea , anxiety , disease , parkinson's disease , antidepressant

Cataplexy is a common symptom associated with narcolepsy. We evaluated a 51-year-old female who developed symptoms of progressive daytime sleepiness with cataplexy. The diagnosis of narcolepsy was confirmed by overnight polysomnogram and was consistent with results of a multiple sleep latency study, and episodes of cataplexy were documented by video-EEG-EMG monitoring. Examination during a catapletic episode was significant for areflexia and paralysis. The frequency of cataplexy increased with fluoxetine, protriptyline and sertraline and the patient developed frank choreiform movements with protriptyline and sertraline. The cataplexy resolved following treatment with carbamazepine. We feel carbamazepine is a potential treatment for patients with refractory cataplexy.

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