eQTLs Weighted Genetic Correlation Analysis Detected Brain Region Differences in Genetic Correlations for Complex Psychiatric Disorders | Zendy

Yan Wen | Zendy; Feng Zhang | Zendy; Xiancang Ma | Zendy; Qianrui Fan | Zendy; Wenyu Wang | Zendy; Jiawen Xu | Zendy; Feng Zhu | Zendy; Jingcan Hao | Zendy; Awen He | Zendy; Li Liu | Zendy; Xiao Liang | Zendy; Yanan Du | Zendy; Ping Li | Zendy; Cuiyan Wu | Zendy; Sen Wang | Zendy; Xi Wang | Zendy; Yujie Ning | Zendy; Xiong Guo | Zendy

Open Access

eQTLs Weighted Genetic Correlation Analysis Detected Brain Region Differences in Genetic Correlations for Complex Psychiatric Disorders

Author(s) -

Yan Wen,

Feng Zhang,

Xiancang Ma,

Qianrui Fan,

Wenyu Wang,

Jiawen Xu,

Feng Zhu,

Jingcan Hao,

Awen He,

Li Liu,

Xiao Liang,

Yanan Du,

Ping Li,

Cuiyan Wu,

Sen Wang,

Xi Wang,

Yujie Ning,

Xiong Guo

Publication year - 2018

Publication title -

schizophrenia bulletin

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.823

H-Index - 190

eISSN - 1745-1707

pISSN - 0586-7614

DOI - 10.1093/schbul/sby080

Subject(s) - genome wide association study , major depressive disorder , schizophrenia (object oriented programming) , bipolar disorder , anterior cingulate cortex , correlation , expression quantitative trait loci , genetic correlation , genetic association , linkage disequilibrium , autism spectrum disorder , psychology , single nucleotide polymorphism , autism , neuroscience , psychiatry , genetics , genotype , genetic variation , biology , gene , cognition , geometry , mathematics

Psychiatric disorders are usually caused by the dysfunction of various brain regions. Incorporating the genetic information of brain regions into correlation analysis can provide novel clues for pathogenetic and therapeutic studies of psychiatric disorders.

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