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Familiality of Psychotic Disorders: A Polynosologic Study in Multiplex Families
Author(s) -
Víctor Peralta,
Ximena Goldberg,
María Ribeiro,
Ana M. Sánchez-Torres,
Lourdes Fañanás,
Manuel J. Cuesta
Publication year - 2015
Publication title -
schizophrenia bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.823
H-Index - 190
eISSN - 1745-1707
pISSN - 0586-7614
DOI - 10.1093/schbul/sbv192
Subject(s) - multiplex , psychology , psychiatry , clinical psychology , medicine , genetics , biology
Phenotype definition of psychotic disorders has a strong impact on the degree of familial aggregation. Nevertheless, the extent to which distinct classification systems affect familial aggregation (ie, familiality) remains an open question. This study was aimed at examining the familiality associated with 4 nosologic systems of psychotic disorders (DSM-IV, ICD-10, Leonhard's classification and a data-driven approach) and their constituting diagnoses in a sample of multiplex families with psychotic disorders.

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