Open AccessInterplay Between Childhood Physical Abuse and Familial Risk in the Onset of Psychotic Disorders
Author(s) -
Helen L. Fisher,
Peter McGuffin,
Jane Boydell,
Paul Fearon,
Tom Craig,
Paola Dazzan,
Kevin Morgan,
Gillian A. Doody,
Peter B. Jones,
Julian Leff,
Robin M. Murray,
Craig Morgan
Publication year - 2014
Publication title -
schizophrenia bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.823
H-Index - 190
eISSN - 1745-1707
pISSN - 0586-7614
DOI - 10.1093/schbul/sbt201
Subject(s) - psychosis , psychiatry , physical abuse , schizophrenia (object oriented programming) , psychology , epidemiology , clinical psychology , medicine , etiology , child abuse , age of onset , poison control , injury prevention , disease , environmental health
Childhood abuse is considered one of the main environmental risk factors for the development of psychotic symptoms and disorders. However, this association could be due to genetic factors influencing exposure to such risky environments or increasing sensitivity to the detrimental impact of abuse. Therefore, using a large epidemiological case-control sample, we explored the interplay between a specific form of childhood abuse and family psychiatric history (a proxy for genetic risk) in the onset of psychosis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom