Distinguishing Prodromal From First-Episode Psychosis Using Neuroanatomical Single-Subject Pattern Recognition
Author(s) -
Stefan Borgwardt,
Nikolaos Koutsouleris,
Jacqueline Aston,
Erich Studerus,
Renata Smieskova,
Anita RiecherRössler,
Eva Meisenzahl
Publication year - 2012
Publication title -
schizophrenia bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.823
H-Index - 190
eISSN - 1745-1707
pISSN - 0586-7614
DOI - 10.1093/schbul/sbs095
Subject(s) - psychosis , psychology , schizophrenia (object oriented programming) , prodromal stage , psychiatry , neuroscience , neuroimaging , clinical psychology , cognition , cognitive impairment
The at-risk mental state for psychosis (ARMS) and the first episode of psychosis have been associated with structural brain abnormalities that could aid in the individualized early recognition of psychosis. However, it is unknown whether the development of these brain alterations predates the clinical deterioration of at-risk individuals, or alternatively, whether it parallels the transition to psychosis at the single-subject level.
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